◀ Back to CA2

CA2 — PIP

Text-mined interactions from Literome

Chen et al., Biochemistry 1999 : The mFc gamma RIIb2 cytoplasmic peptide does not bind, in the presence or absence of Ca2+ , to PS/PC, PIP2/PC , or PC vesicles
Ohizumi et al., Can J Physiol Pharmacol 1999 : PIP2 caused a concentration dependent increase in Ca2+ release from SR of chemically skinned fibers from skeletal muscle
Tucker et al., J Cell Biol 2003 : These data suggest that syts trigger fusion via their Ca2+ regulated interactions with t-SNAREs and PIP2 , target molecules known to play critical roles in exocytosis
Rebecchi et al., Biochemistry 1992 : The binding strength increased further ( Ka congruent to 10 ( 6 ) M-1 ) when the vesicles also contained 30 % PS. High-affinity binding of PLC-delta to PIP2 did not require Ca2+
Huang et al., J Biol Chem 1991 : The PIP2 bound PKC could further interact with phosphatidylserine in the presence of Ca2+ to form a larger complex ... Binding of PKC to both PIP2 and phosphatidylserine in the presence of Ca2+ was also evident by changes in the intrinsic fluorescence of PKC
Vasudevan et al., J Cell Sci 2009 (Calcium Signaling) : In summary, PIP5K-I gamma positively regulates antigen stimulated Ca2+ release from ER stores, whereas PIP5K-I beta negatively regulates store operated Ca2+ entry, suggesting that these different PIP5K-I isoforms synthesize functionally distinct pools of PtdIns ( 4,5 ) P2 at the plasma membrane
Kobayashi et al., Biochem Biophys Res Commun 1989 : PIP2 enhanced the caffeine induced Ca2+ release from SR vesicles at low concentrations and triggered Ca2+ release by itself at high concentrations
Schwertz et al., Arch Biochem Biophys 1989 : In the presence of Ca2+ , addition of Mg2+, La3+, or Sr2+ ( 10 ( -3 ) M ) inhibited PIP2-PLC while Mn2+ and Gd3+ stimulated activity
Strosznajder et al., Neurochem Res 1989 : In the presence of EGTA PIP2 was actively degraded, opposite to PI and PIP which require Ca2+ for their hydrolysis
Giraud et al., Biochim Biophys Acta 1988 : PMA treatment had no effect on the Ca2+ dependent PIP/PIP2 phospholipase C activity measured in isolated membranes
Mack et al., Biochem Cell Biol 1988 : A low Ca2+ dependent PIP2 phosphatase activity, not present in other tissues, was also detected ... Ca2+ dependent PIP2 phosphatase activity is not correlated with the activity or subcellular distribution of any of the other hydrolases and seems to be a separate enzyme
Quist et al., Arch Biochem Biophys 1985 : MgCl2 inhibited the rate of Ca2+ stimulated breakdown of PIP and PIP2 at Ca2+ concentrations less than 10 microM, but did not have any appreciable effects at higher Ca2+ concentrations
Sasaguri et al., Biochem J 1985 : The addition of 1 mM-MgCl2 to the assay medium markedly inhibited the activity of PIP2 PDE in both fractions in the presence of free Ca2+ ( 10 ( -8 ) -10 ( -5 ) M )
Magnaldo et al., FEBS Lett 1987 : A Ca2+ dependent PIP2 and PIP phospholipase C activity was characterized by measuring the rate of formation of inositol tris- and bisphosphate
Nakamura et al., Endocrinology 1987 : After the release induced by a maximal amount of IP3, PIP2 could induce a further Ca2+ release
Banerjee et al., Hum Reprod 1995 : The SABP also induces an increase in intracellular Ca2+ in spermatozoa, as seen by FURA-2 AM studies
Kardasz et al., Eur J Endocrinol 1997 : There was no effect of 10 ( -6 ) mol/l Ca2+ on the levels of PIP and PIP2
Lin et al., J Biol Chem 1997 : We present evidence that PIP2 binding to the gelsolin family of capping proteins is enhanced by Ca2+