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UCSC Genome Browser Gene Interaction Graph
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Gene interactions and pathways from curated databases and text-mining
◀ Back to FKBP5
FKBP5 — PPP5C
Pathways - manually collected, often from reviews:
NCI Pathway Database Glucocorticoid receptor regulatory network :
GR alpha/HSP90/FKBP51/HSP90/PP5C complex (NR3C1-HSP90AA1-FKBP5-PPP5C)
→
PP5C (PPP5C)
(modification, collaborate)
Russell et al., J Biol Chem 1999 * , Chen et al., J Biol Chem 1996 *
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Glucocorticoid receptor regulatory network :
GR alpha/HSP90/FKBP51/HSP90/PP5C complex (NR3C1-HSP90AA1-FKBP5-PPP5C)
→
GR alpha/HSP90/FKBP51/HSP90 complex (NR3C1-HSP90AA1-FKBP5)
(modification, collaborate)
Russell et al., J Biol Chem 1999 * , Chen et al., J Biol Chem 1996 *
Evidence: mutant phenotype, assay, physical interaction
NCI Pathway Database Glucocorticoid receptor regulatory network :
PP5C (PPP5C)
→
GR alpha/HSP90/FKBP51/HSP90 complex (NR3C1-HSP90AA1-FKBP5)
(modification, collaborate)
Russell et al., J Biol Chem 1999 * , Chen et al., J Biol Chem 1996 *
Evidence: mutant phenotype, assay, physical interaction
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
IRef Intact Interaction :
Complex of 15 proteins
(physical association, anti tag coimmunoprecipitation)
Sowa et al., Cell 2009
IRef Intact Interaction :
Complex of 33 proteins
(association, tandem affinity purification)
Gano et al., Mol Cell Proteomics 2010
IRef Intact Interaction :
Complex of 20 proteins
(association, tandem affinity purification)
Gano et al., Mol Cell Proteomics 2010
IRef Intact Interaction :
Complex of 34 proteins
(physical association, anti tag coimmunoprecipitation)
Sowa et al., Cell 2009
IRef Intact Interaction :
Complex of 29 proteins
(association, tandem affinity purification)
Gano et al., Mol Cell Proteomics 2010
IRef Intact Interaction :
Complex of 46 proteins
(association, tandem affinity purification)
Gano et al., Mol Cell Proteomics 2010