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ELAVL1 — TP53

Text-mined interactions from Literome

Galbán et al., Mol Cell Biol 2003 (Carcinoma, Renal Cell...) : Demonstration that HuR indeed contributed to the increased expression of p53 in VHL ( + ) cells was obtained through use of RNA interference, which effectively reduced HuR expression and in turn caused marked decreases in p53 translation and p53 abundance
Tong et al., Mol Carcinog 2009 : Overexpression of HuR enhanced apigenin induced p53 protein expression in 308 keratinocytes, whereas siRNA mediated HuR reduction suppressed apigenin induced p53 protein expression and de novo translation of p53
Lee et al., Mol Cells 2012 : Accumulation of HuR in the cytoplasm, in turn, enhances the expression of the transcription factor p53 , a tumor suppressor that plays an essential role in preserving genome stability and inhibiting cancer growth