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GHR — NOS3
Text-mined interactions from Literome
Egecioglu et al., Am J Physiol Endocrinol Metab 2007
:
Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin,
increased aortic
eNOS expression, and altered cardiovascular structure and function ... In conclusion, loss of
GHR leads to low BP and decreased levels of renin in plasma as well as
increase in aortic
eNOS expression
Yang et al., Peptides 2013
:
Moreover, the
Ghr ( 10 ( -7 ) mol/l ) significantly
increased NO secretion and
eNOS phosphorylation in comparison with the hypoxia or normoxia alone group ( P < 0.05, n=4 ) ... Nevertheless, the treatment with LY294002 ( 20µmol/l ) decreased the
Ghr induced NO release as well as the
eNOS activity