UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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ESR2 — GNA15

Pathways - manually collected, often from reviews:

NCI Pathway Database Plasma membrane estrogen receptor signaling: E2/ERA-ERB (dimer) complex (ESR2_ESR1) → Gq family/GTP complex (GNA11_GNAQ_GNA15_GNA14) (modification, activates)
Razandi et al., Mol Endocrinol 2004, Razandi et al., Mol Endocrinol 1999
Evidence: mutant phenotype, assay, other species
NCI Pathway Database Plasma membrane estrogen receptor signaling: E2/ERA-ERB (dimer) complex (ESR2_ESR1) → Gq family/GDP/Gbeta gamma complex (GNA11_GNAQ_GNA15_GNA14-GNB1-GNG2) (modification, activates)
Razandi et al., Mol Endocrinol 2004, Razandi et al., Mol Endocrinol 1999
Evidence: mutant phenotype, assay, other species