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CCL4 — IL8
Text-mined interactions from Literome
Krzysiek et al., J Immunol 1999
:
Culturing follicular dendritic cell-like HK cells with activated B cells did not regulate
MIP-1 alpha/beta production, but it did
induce production of
IL-8 by HK cells
Waehre et al., J Am Coll Cardiol 2003
(Coronary Artery Disease) :
Our main findings were : 1 ) gene expression of several chemokines ( i.e., macrophage inflammatory protein [MIP ] -1alpha,
MIP-1beta , and interleukin [ IL]-8 ) and chemokine receptors ( i.e., CC chemokine receptor [ CCR]1, CCR2, CCR4, and CCR5 ) was markedly increased among CAD patients compared with healthy control subjects ; 2 ) treatment with atorvastatin and simvastatin markedly
reduced the mRNA levels of some of these chemokines ( i.e., MIP-1alpha, MIP-1beta, IL-8 ) and receptors ( i.e., CCR1 and CCR2 ), with the most pronounced effect in the atorvastatin group ; and 3 ) statin therapy reduced the spontaneous release of
IL-8 and MIP-1alpha from PBMCs in CAD patients