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GDF15 — IFI44

Text-mined interactions from Literome

Baliga et al., Am J Physiol 1999 (Cardiomegaly) : NRG-1 activated p42/p44 mitogen activated protein kinase ( MAPK ) [ extracellular signal regulated kinase ( ERK ) -2/ERK1 ] and ribosomal S6 kinase (RSK)-2 ( 90-kDa ribosomal S6 kinase ), both of which could be inhibited by the MAPK/ERK kinase-1 antagonist PD-098059
Gerecke et al., Mol Cell Neurosci 2004 : NRG-1beta effects on neurite extension and arborization are similar to, but not additive with, those of brain derived neurotrophic factor and reflect direct NRG-1 action on hippocampal neurons as these cells express the NRG-1 receptors erbB2 and erbB4, the erbB-specific inhibitor PD158780 decreases NRG-1beta induced neurite outgrowth, and NRG-1beta stimulation induces p42/44 ERK phosphorylation