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BMP7 — PRG3

Text-mined interactions from Literome

Loeser et al., J Rheumatol 2003 (Osteoarthritis) : In contrast, compared to controls, OP-1 at 100 ng/ml stimulated a 3-fold increase in matrix proteoglycan at day 21 of culture
Zhang et al., Am J Phys Med Rehabil 2004 : OP-1 stimulates proteoglycan accumulation by bovine IVD cells isolated from all three zones of the bovine IVDs
Zhang et al., Am J Phys Med Rehabil 2005 : Low-dose interleukin-1 partially counteracts osteogenic protein-1 induced proteoglycan synthesis by adult bovine intervertebral disk cells
Flechtenmacher et al., Arthritis Rheum 1996 : To study the effects of recombinant human osteogenic protein-1 ( rHuOP-1 ; bone morphogenetic protein-7 ) on proteoglycan and collagen synthesis by human articular chondrocytes
Lietman et al., J Bone Joint Surg Am 1997 : Stimulation of proteoglycan synthesis in explants of porcine articular cartilage by recombinant osteogenic protein-1 ( bone morphogenetic protein-7 ) ... The stimulation of proteoglycan synthesis by osteogenic protein-1 ( bone morphogenetic protein-7 ) in explants of cartilage maintained in chemically defined serum-free medium implies that recombinant osteogenic protein-1 may play a role in the maintenance of a steady-state concentration of proteoglycans in articular cartilage, a desirable prerequisite for optimum repair of cartilage
Wu et al., J Cell Biochem 1997 : Alone, OP-1 caused approximately 2-fold increase in proteoglycan synthesis into both the medium and the cell : matrix layer
Huch et al., Arthritis Rheum 1997 : Effects of recombinant human osteogenic protein 1 on the production of proteoglycan , prostaglandin E2, and interleukin-1 receptor antagonist by human articular chondrocytes cultured in the presence of interleukin-1beta