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ATF3 — GNRH1
Text-mined interactions from Literome
Xie et al., Endocrinology 2008
(MAP Kinase Signaling System) :
3 ', 5'-cyclic adenosine 5'-monophosphate response element dependent transcriptional regulation of the secretogranin II gene promoter depends on
gonadotropin releasing hormone induced mitogen activated protein kinase activation and the transactivator
activating transcription factor 3
Mayer et al., Endocrinology 2008
:
Stimulation of
GnRH receptors
enhances expression of
activating transcription factor (ATF) 3 in a pituitary gonadotroph cell line
Salisbury et al., Mol Endocrinol 2009
:
GnRH regulates gonadotrope function through a complex transcriptional network that includes three members of the immediate early gene family : Egr1, Jun, and
Atf3
Binder et al., Mol Endocrinol 2012
(Calcium Signaling) :
GnRH regulation of Jun and
Atf3 requires calcium, calcineurin, and NFAT ... Additionally, although small interfering RNA specific for Nfat4 only marginally reduced
GnRH regulation of Jun, Fos, and
Atf3 mRNA accumulation, activity of an activator protein-1-responsive reporter construct was reduced by 48 %