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MSK10 — WNK1

Text-mined interactions from Literome

Vanden Berghe et al., Cancer Res 2006 (MAP Kinase Signaling System) : This occurs via attenuation of mitogen activated protein/extracellular signal regulated kinase ( ERK ) kinase ( MEK ) and ERK activity, which further down-regulates MSK dependent NF-kappaB p65 and histone H3 phosphorylation
Joo et al., J Biol Chem 2008 (Lung Neoplasms) : We further show that inhibition of MSK1 , a kinase acting downstream of MEK1/2-ERK1/2, by H89 or knockdown of MSK1 expression also inhibited phosphorylation of p65/RelA ( Ser ( 276 ) ), suggesting that this phosphorylation is dependent on MSK1
Reber et al., PloS one 2009 (Inflammation) : We show here that the MAPK downstream nuclear kinase MSK1 induces NF-kappaB p65 Ser276 phosphorylation upon IL-1beta treatment, which was inhibited in cells transfected with a MSK1 kinase-dead ( KD ) mutant compared to the WT control
Yang et al., Free Radic Biol Med 2011 : Like a JNK inhibitor, darbepoetin alfa did not affect I?Ba degradation or p65 nuclear translocation, but did inhibit mitogen- and stress activated protein kinase 1 ( MSK1 ) activation and attenuated p65 phosphorylation ( serine 276 ), effects that may account for the reduction in NF-?B DNA binding activity