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IL1RN — PIK3R1
Text-mined interactions from Literome
O'Connor et al., J Immunol 2007
(Diabetes Mellitus, Type 2) :
Inhibition of
PI3K with wortmannin or blockage of IRS-2/PI3K complex formation with a cell permeable IRS-2 derived tyrosine phosphopeptide
inhibited IL-4 dependent
IL-1RA production in db/+ macrophages
Corbett et al., J Immunol 2012
(Neurodegenerative Diseases) :
Activation of type IA p110a PI3K and Akt by gem and abrogation of gem induced
upregulation of
IL-1Ra by inhibitors of
PI3K and Akt indicate a role of the PI3K-Akt pathway in the upregulation of IL-1Ra