Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
ERBB3
→
IL6
(increases)
Qiu et al., Nature 1998* Evidence: When LNCaP cells were treated with IL6 Erbb3 and Erbb2 proteins were tyrosine phosphorylated. With them all the three isoforms of Shc proteins were also phosphorylated.
OpenBEL Selventa BEL large corpus:
ERBB3
→
IL6
(increases)
Qiu et al., Nature 1998* Evidence: treatment of the prostate cancer cell line LNCaP with IL-6 induces tyrosine phosphorylation of ErbB2 and ErbB3, but not ErbB1/EGFR. We also show that ErbB2 forms a complex with the gp130 subunit of the IL-6 receptor