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CD4 — CTNNB1
Text-mined interactions from Literome
Huang et al., J Immunol 2006
:
Furthermore, forced expression of a stabilized
beta-catenin , a coactivator of TCF-1,
resulted in up-regulation of
CD4
Yu et al., J Immunol 2007
:
Previously, we have shown that expression of stabilized
beta-catenin , the major transcriptional cofactor of T cell factor,
results in increase in both
CD4SP and CD8SP thymocytes with a preferential effect on CD8SP thymocytes
Schenkel et al., J Immunol 2010
:
Beta-catenin signaling
mediates CD4 expression on mature CD8+ T cells ... Activation of
beta-catenin signaling, through LiCl or transfection with a constitutively active construct of beta-catenin,
induced CD4 on CD8 ( + ) T cells by approximately 10-fold ...
Beta-catenin mediated induction of
CD4 on CD8 ( + ) T cells is transcriptionally regulated, as it induced CD4 mRNA, and T cell factor/lymphoid enhancer factor sites were identified within the human CD4 promoter