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CTNNB1 — GAST

Text-mined interactions from Literome

Koh et al., J Clin Invest 2000 (Adenomatous Polyposis Coli...) : Activation of gastrin by beta-catenin may therefore represent an early event in colorectal tumorigenesis and may contribute significantly toward neoplastic progression
Hollande et al., J Biol Chem 2001 : Furthermore, glycine extended gastrin ( 17 ) induced a PI3-kinase mediated tyrosine phosphorylation of the adherens junction protein beta-catenin , partial dissociation of the complex between beta-catenin and the transmembrane protein E-cadherin, and delocalization of beta-catenin into the cytoplasm
Chakladar et al., Biochem Biophys Res Commun 2005 : Synergistic activation of the murine gastrin promoter by oncogenic Ras and beta-catenin involves SMAD recruitment
Cao et al., World J Gastroenterol 2006 (Colonic Neoplasms) : To explore the effect of gastrin 17 (G17) on beta-catenin/T cell factor-4 (Tcf-4) signaling in colonic cancer cell line Colo320WT ... Gastrin17 activates beta-catenin/Tcf-4 signaling in Colo320WT cells, thereby leading to over-expression of c-myc and cyclin D1
He et al., Biochim Biophys Acta 2008 : A kinase-inactive mutant PAK1 ( K299A ) blocked the gastrin stimulated dissociation of beta-catenin from E-cadherin, translocation of beta-catenin from the cell membrane to the nucleus, and association of beta-catenin with the transcription factor TCF4