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ETS1 — SLC22A3
Text-mined interactions from Literome
Taki et al., Int J Oncol 2006
(Carcinoma, Squamous Cell...) :
These results indicate that
EMT induces
Ets-1 expression, which activates the MMP-2 promoter, but Ets-1 by itself has no activity to induce EMT in SCC cells
Shirakihara et al., Mol Biol Cell 2007
:
Taken together, these findings suggest that the deltaEF1 family proteins, SIP1 and deltaEF1, are necessary, but not
sufficient , for TGF-beta induced
EMT and that
Ets1 induced by TGF-beta may function as an upstream transcriptional regulator of SIP1 and deltaEF1