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ELAVL1 — TNF

Text-mined interactions from Literome

McMullen et al., J Biol Chem 2003 : Further, we show that HuR , a nuclear/cytoplasmic shuttling protein, which binds to TNFalpha mRNA, is required for increased expression of TNFalpha after chronic ethanol ... Taken together, these data demonstrate that increased binding of HuR to the TNFalpha 3'-UTR contributes to increased LPS stimulated TNFalpha expression in macrophages after chronic ethanol exposure
Nagy et al., Alcohol 2004 : Moreover, results from studies have demonstrated that at least one mRNA binding protein, HuR , is also involved in stabilization of TNF-alpha mRNA stability after chronic exposure to ethanol
Suzuki et al., Int J Mol Med 2006 (Arthritis, Rheumatoid...) : While HuR stabilizes TNF-alpha mRNA and enhances TNF-alpha production, TIA-1 acts as a post-transcriptional silencer, and suppresses the production of the TNF-alpha protein
Zha et al., PloS one 2010 : Berberine significantly inhibited HIV PI-induced TNF-alpha and IL-6 expression by modulating ER stress signaling pathways and subsequent ERK activation, in turn preventing the accumulation of the RNA binding protein HuR in cytosol and inhibiting the binding of HuR to the 3'-UTRs of TNF-alpha and IL-6 in macrophages