◀ Back to CDH1

CDH1 — UBE2D1

Text-mined interactions from Literome

Kramer et al., Mol Biol Cell 2000 : The ordered activation of the ubiquitin protein ligase anaphase promoting complex (APC) or cyclosome by CDC20 in metaphase and by CDH1 in telophase is essential for anaphase and for exit from mitosis, respectively
Pfleger et al., Genes Dev 2001 : Despite evidence showing that Cdc20 and Cdh1 bind and activate the anaphase promoting complex (APC) in a substrate-specific manner, there is no evidence that the activating protein and substrate interact directly ; hence, no clear model exists for the mechanism of APC activation or recruitment of substrates
Wan et al., Proc Natl Acad Sci U S A 2001 : CDC20/CDH1 activates the anaphase promoting complex (APC) and targets various substrates for degradation, thereby allowing the ordered progression through mitosis and G ( 1 )
Zhou et al., Biochem Biophys Res Commun 2002 : The anaphase promoting complex (APC) is a major component of this degradation machinery and its activation is regulated by CDC20 and CDH1
Zhou et al., J Biol Chem 2003 : The anaphase promoting complex activated by CDC20 and CDH1 is a major ubiquitination system that controls the destruction of cell cycle regulators
Kraft et al., Mol Cell 2005 : Activation of the anaphase promoting complex/cyclosome ( APC/C ) by Cdc20 and Cdh1 leads to ubiquitin dependent degradation of securin and cyclin B and thereby promotes the initiation of anaphase and exit from mitosis
Reis et al., Nat Cell Biol 2006 : Cdh1 is an activator of the anaphase promoting complex (APC) and APCcdh1 is normally restricted to late M to early G1 phases of the cell cycle
Martinez et al., Mol Cell Biol 2006 : Acm1 is a negative regulator of the CDH1 dependent anaphase promoting complex/cyclosome in budding yeast
Medendorp et al., PloS one 2009 : Although MAD2B is thought to inhibit the anaphase promoting complex (APC) by binding to CDC20 and/or CDH1 ( FZR1 ), its exact role in cell cycle control still remains to be established
Wäsch et al., Oncogene 2010 (Genomic Instability...) : The anaphase promoting complex or cyclosome ( APC/C ) activated by Cdh1 coordinately eliminates positive cell-cycle regulators as well as inhibitors of differentiation, thereby coupling cell-cycle exit and differentiation
Naoe et al., Mol Cell Biol 2010 : Cdh1 is an activator of the anaphase promoting complex/cyclosome and contributes to mitotic exit and G ( 1 ) maintenance by targeting cell cycle proteins for degradation
Medendorp et al., PloS one 2010 : Although the mitotic arrest deficient protein MAD2B ( MAD2L2 ) is thought to inhibit the anaphase promoting complex (APC) by binding to CDC20 and/or CDH1 ( FZR1 ), its exact role in cell cycle control still remains to be established
Naoe et al., Biochem Biophys Res Commun 2013 : Here, we report that Cdh1 , a regulator of the anaphase promoting complex/cyclosome ( APC/C ), negatively regulates mitotic entry upon the mitotic/endocycle transition
Fang et al., Genes Dev 1998 : Activation of the anaphase promoting complex (APC) by binding of CDC20 and CDH1 is required for exit from mitosis, and APC has been implicated as a target for the checkpoint intervention