McManus et al., J Biol Chem 2000
:
Transformation-specific, tyrosine phosphorylation of Pak enhances the catalytic activity of this serine/threonine kinase Deguchi et al., J Biol Chem 2010
(Neoplasms) :
The knockdown of LKB1 enhanced cell migration and PAK1 activity in human colon cancer HCT116 cells, whereas forced expression of LKB1 in Lkb1-null mouse embryonic fibroblasts suppressed PAK1 activity and PAK1 mediated cell migration simultaneously