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IFNG — PRL

Text-mined interactions from Literome

Matera et al., Immunology 1999 : Released and intracellular IFN-gamma , as well as IFN-gamma mRNA expression, were increased by pituitary and recombinant human PRL , which stimulated optimal NK and LAK cytotoxicity
Matera et al., Ann N Y Acad Sci 2000 : We have extended that study by exploring the ability of PRL to induce IFN-gamma production by T and NK cells in the presence of the specific stimuli IL-12 and IL-2
Breidthardt et al., Immunobiology 2002 (Hyperprolactinemia) : Prolactin induces enhanced interferon gamma release in peripheral whole blood after stimulation with either PHA or LPS
Matalka et al., Cytokine 2003 : Prolactin enhances production of interferon-gamma , interleukin-12, and interleukin-10, but not of tumor necrosis factor-alpha, in a stimulus-specific manner
Dimitrov et al., Brain Behav Immun 2004 : The following changes reached significance ( p < .05 ) : prolactin ( versus prolactin antibody ) increased tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) producing CD4+ and CD8+ cells and interleukin-2 (IL-2) producing CD8+ cells
Lau et al., Immunol Lett 2006 (Diabetes Mellitus, Experimental) : Prolactin regulation of the expression of TNF-alpha, IFN-gamma and IL-10 by splenocytes in murine multiple low dose streptozotocin diabetes
Yamaguchi et al., J Endocrinol Invest 1991 : The effects of interferon-alpha, interferon-beta 1 and interferon-gamma on the secretions of prolactin (PRL) and interleukin-6 by primary cultured rat anterior pituitary cells were examined
Kanda et al., Endocrinology 2007 (MAP Kinase Signaling System...) : Prolactin induced phosphorylation of JAK2 and ERK, whereas IFN-gamma induced phosphorylation of JAK1, JAK2, and p38 MAPK
Tripathi et al., Int Immunol 2008 : Further, pre-treatment of macrophages with SP600125 inhibited the PRL induced production of IFN-gamma and TNF-alpha ... AG490, inhibitor of JAK2, down-regulated transcription factors c-jun and STAT1 and inhibited the PRL induced IFN-gamma , TNF-alpha, IL-1 beta and IL-12p40 production in macrophages
Walton et al., Am J Physiol 1990 : Tumor necrosis factor-alpha and interferon-gamma reduce prolactin release in vitro
Galdiero et al., Eur Cytokine Netw 1995 : Effect of growth hormone, prolactin and insulin on the release of IL-1 alpha, IFN-gamma and IL-4 by staphylococcal enterotoxin A-stimulated splenocytes
Vitiello et al., Immunol Cell Biol 1995 : Prolactin and insulin regulate the release of IL-1-alpha and IFN-gamma from murine splenocytes activated with porins or LPS of Salmonella typhimurium ... It was seen that PRL inhibits the release of IFN-gamma from splenocytes treated with porins by about 20 % while having no effect on the release of IL-1-alpha
Scarfogliero et al., New Microbiol 1996 : Prolactin regulates IL-1 alpha, IFN-gamma and IL-4 release from mouse splenocytes stimulated with some staphylococcal and streptococcal toxins ... In the presence of PRL , IL-1 alpha and IFN-gamma induction by PA-stimulated splenocytes was reduced by 74 % and 25 % respectively ... In the presence of PRL , IFN-gamma release from splenocytes stimulated with SLS, was increased by 60 %, while no changes were shown in IL-1 alpha and IL-4 release
Vankelecom et al., Mol Cell Endocrinol 1997 : Involvement of nitric oxide in the interferon-gamma induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures ... L-N6- ( 1-iminoethyl ) lysine ( L-NIL ), a NOS inhibitor with preferential affinity for iNOS, abrogated the IFN-gamma effect on GHRH stimulated GH secretion and partially reversed IFN-gamma inhibition of PRL release ... It is concluded that IFN-gamma through activation of the iNOS pathway probably in FS cells enhances the production of NO and that this effect is responsible for the inhibitory action of IFN-gamma on GHRH stimulated GH release and partially for the IFN-gamma induced decrease in basal PRL release
Richards et al., Cell Immunol 1998 (HIV Infections...) : Prolactin enhances the proliferative response of lymphoid cells to both nonspecific mitogens and specific antigens and increases their production of IL-2 and interferon-gamma