Kukreja et al., Cancer Res 2005
(Bone Neoplasms...) :
Suppression of NF-kappaB activity in PC-3 cells by a mutant IkappaBalpha super-repressor adenoviral vector decreased the CXCR4 mRNA expression and inhibited adhesion and TEM Zabel et al., J Immunol 2009
:
Using CCX771, a novel small molecule with high affinity and selectivity for CXCR7, we found that, although CXCR7 is dispensable for `` bare filter '' in vitro chemotaxis, CXCR7 plays an essential role in the CXCL12/CXCR4 mediated transendothelial migration (TEM) of CXCR4 ( + ) CXCR7 ( + ) human tumor cells