Gene interactions and pathways from curated databases and text-mining

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IL6 — NPPA

Text-mined interactions from Literome

Tanaka et al., Res Commun Mol Pathol Pharmacol 2001 (Body Weight...) : Primary cultures of neonatal rat cardiac myocyte showed that IL-6 increased ANP and BNP mRNA expression in a dose-responsive fashion
Tanaka et al., J Int Med Res 2004 : We investigated the effect of interleukin-6 (IL-6) expression on sarco/endoplasmic reticulum Ca ( 2+ ) -ATPase ( SERCA ), atrial natriuretic peptide (ANP) and B-type natriuretic peptide ( BNP ) mRNA levels in cultured rat neonatal ventricular myocytes
Moro et al., Diabetologia 2007 (Inflammation...) : ANP directly inhibited the secretion of IL-6 and monocyte chemoattractant protein-1 by macrophages
Turkyilmaz et al., Inflammation 2007 (Disease Models, Animal...) : The induction of ANP resulted in a significant increase in the mortality rate, pancreatic necrosis, serum activity of amylase, alanine aminotransferase ( ALT ), and interleukin-6 (IL-6) , lactate dehydrogenase ( LDH ) in bronchoalveolar lavage (BAL) fluid, serum concentration of urea, and tissue activity of myeloperoxidase (MPO) and maondialdehyde ( MDA ) in the pancreas and lung, and a significant decrease in concentrations of calcium, blood pressure, urine output and p0 ( 2 )
Walsh et al., Cancer Biol Ther 2010 (Breast Neoplasms...) : In vitro, PND-1186 reduced tumor necrosis factor-a triggered interleukin-6 cytokine expression, indicating that FAK inhibition may impact tumor progression via effects on both tumor and stromal cells