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IL6 — PCK2

Text-mined interactions from Literome

Leroyer et al., J Lipid Res 2011 (Inflammation) : IL-6 ( 100 ng ) inhibited the activity of phosphoenolpyruvate carboxykinase , the key enzyme of glyceroneogenesis, in SAT but not in VAT
Christ et al., Hepatology 1997 : This showed that IL-6 inhibited PCK mRNA increase in part by the attenuation of cAMP increase, but also beyond cAMP formation ... It is concluded that IL-6 had a dual inhibitory effect on the stimulation of PCK gene expression by glucagon