Yang et al., Exp Eye Res 2010
:
On the other hand, the TRPV1 mediated increases in IL-6 and IL-8 release are elicited through both EGFR dependent and EGFR independent signaling pathways
Pan et al., Invest Ophthalmol Vis Sci 2011
:
ELISA assessed the effect of TRPV1 activation on the release of IL-6 and IL-8 ... Hypertonic stress elicited TRPV1 channel stimulation mediates increases in a proinflammatory cytokine IL-6 and a chemoattractant IL-8 by eliciting EGFR transactivation, MAPK, and NF-?B activation
Wang et al., Molecular vision 2011
(MAP Kinase Signaling System) :
TRPV1 induced increases in IL-6/IL-8 release occur through TAK1 activation of JNK1 dependent and JNK1 independent signaling pathways