Gene interactions and pathways from curated databases and text-mining

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PTX4 — SERPINE1

Text-mined interactions from Literome

Cigolini et al., Atherosclerosis 1999 (Obesity) : PTX caused a dose dependent decrease of basal PAI-1 protein release, reaching 80 % maximal inhibitory effect at 10 ( -3 ) M, the same inhibitory effect caused by Genistein at 100 microg/ml
Rydholm et al., Scand J Clin Lab Invest 1998 : Pertussis toxin ( PTX ) ( inhibiting Galpha i-pathway ) reduced basal PAI-1 ( 66 +/- 8 % ), but had only a weak influence on basal t-PA production