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NOS2 — SNAP25

Text-mined interactions from Literome

Chen et al., J Cell Physiol 2001 : Between 4 and 8 h, SNAP and NONOate caused a 2- to 3-fold increase in eNOS, but not iNOS , gene ( P < 0.05 ) and protein expression
Hsu et al., Shock 2002 (Reperfusion Injury) : On the contrary, the NO donor SNAP increased the activity of iNOS and decreased the hepatic injury in this study
Mendes et al., Inflamm Res 2002 : SNAP inhibited IL-I induced NF-kappaB activation and NOS II expression
Chang et al., Exp Mol Med 2004 : SNAP also blocked cytokine- induced increase in NF-kappaB activation, iNOS promoter activity, nuclear translocation of cytosolic NF-kappaB p65 subunit, and IkappaBalpha degradation, which correlated with its inhibitory effect on phosphorylation and ubiquitination of IkappaB
Sosroseno et al., Anaerobe 2009 : The results showed that in A. actinomycetemcomitans LPS stimulated cells, SNAP enhances iNOS activity but inhibits the levels of specific IgG2a and IFN-gamma suggesting a Th1 response