Gene interactions and pathways from curated databases and text-mining

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IRF6 — NOD1

Text-mined interactions from Literome

Kim et al., J Immunol 2008 (MAP Kinase Signaling System...) : These changes were accompanied by the suppression of the LPS induced expression of TLR4, NOD1 , and NOD2, and the induction of IRAK-M, with a concurrent reduction of TNF-alpha secretion
Mulla et al., Am J Reprod Immunol 2009 : This study demonstrates that LPS , through TLR4, increases trophoblast expression of Nod1 and Nod2 via the NFkappaB pathway ; and that Nod1 is functional in the trophoblast
Shimizu et al., Toxicol In Vitro 2012 (Bacterial Infections...) : LPS inhibited the expression of TLR4, CD14, MD2 and NOD1 genes in FSH treated granulosa cells from small follicles
Lappas et al., Biol Reprod 2013 : The aims of this study were to determine the effect of 1 ) human labor, proinflammatory cytokines, and bacterial endotoxin LPS on NOD1 and NOD2 expression and 2 ) NOD1 and NOD2 activation on the expression of prolabor mediators in human fetal membranes and myometrium