Ahmed et al., Am J Physiol Gastrointest Liver Physiol 2006
:
TNF attenuated JAK2/STAT5 and ERK1/2 phosphorylation and IGF-I and Spi 2.1 mRNA expression following GH stimulation ... TNF prevented the induction of Spi 2.1 promoter activity by GH and the STAT5 construct
Blois et al., Regul Pept 2006
:
Here we report on the effect of recombinant human CgA1-78 , vasostatin-I, on TNFalpha induced gap formation in two model systems of vascular leakage in arterial endothelial cells of bovine pulmonary ( BPAEC ) and coronary ( BCAEC ) origin
Buzzelli et al., Endocrinology 2008
:
The 5- to 6-fold induction of Spi 2.1 and IGF-I promoter activity by GH was inhibited by TNF ... IkappaBalphaS/A and IkappaBalphaTrunc ameliorated the inhibitory effects of TNF on GH-inducible Spi 2.1 and IGF-I promoter activity
Yanaka et al., Mol Nutr Food Res 2011
(Colonic Neoplasms...) :
This study also showed that tumor necrosis factor a (TNF-a) induced SPI-3 mRNA expression in HT-29 human colon cancer cells, and vitamin B6 ( pyridoxal hydrochloride ) pretreatment of HT-29 cells inhibited TNF -induced mRNA expression of SPI-3