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IRF6 — PTPN11

Text-mined interactions from Literome

Abschuetz et al., Cell Tissue Res 2006 (Glioma) : Moreover, stimulation with LPS and/or IFN-gamma resulted in a decreased expression of the viral replicative and cytotoxic protein NS1
Orr et al., Blood 2007 (Inflammation) : Suppressor of cytokine signaling 3 ( SOCS3 ) is expressed in response to cytokines, LPS , and other PAMPs, and competes with SHP-1/2 binding to ITIMs of cytokine receptors, thereby inhibiting signaling
Miyake et al., Genes Cells 2008 : These results suggest that LPS or poly ( I : C ) induces tyrosine phosphorylation of SHPS-1 and the association of SHPS-1 with SHP-1 and SHP-2 in a manner dependent on a Src family kinase
Chen et al., J Cell Biochem 2010 (Inflammation) : We next observed that integrin beta4 silencing increased basal and LPS induced phosphorylation of SHP-2 , a protein tyrosine phosphatase known to modulate MAPK signaling