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IFNG — TAP2

Text-mined interactions from Literome

Lee et al., Cancer Res 2000 (Neoplasm Metastasis...) : IFN-gamma induced surface class I MHC expression, as well as gene expression of TAP-1, TAP-2 , LMP-2, and LMP-7 in the metastatic cells, yet the cells remained resistant to cell lysis induced by CTLs. Interestingly, although in comparison to the primary cells the metastatic cells were resistant to cytolysis, both cell types were susceptible to DNA fragmentation induced by CTLs. Cell fusion between primary and metastatic cancer cells resulted in hybrids that also resisted the cytolytic activity of CTLs
Guo et al., Int Immunol 2002 : Moreover, while the TAP-2 promoter region contains cis elements that can mediate TAP-2 induction by IFN-gamma , such as gamma-activation site and IFN response factor binding element ( IRFE ), only the IRFE is required for IFN-gamma induction of TAP-2 promoter in vitro
Sanda et al., J Natl Cancer Inst 1995 (Prostatic Neoplasms) : Induction of TAP-2 by interferon gamma indicated that coding sequences for TAP-2 message were present in PPC-1
Kuroda et al., Immunology 1995 (Fibrosarcoma) : Interferon-gamma (IFN-gamma) treatment of these cells induced expression of Kk, TAP1 and TAP2 genes and rescued the defect of class I-restricted antigen presentation in 4C2 and 6D1 cells