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HSPA5 — RELA

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Intact Interaction: HSPA5 — RELA (physical association, tandem affinity purification) Bouwmeester et al., Nat Cell Biol 2004
• IRef Ophid Interaction: HSPA5 — RELA (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Yamazaki et al., J Immunol 2009 : Following the degradation of GRP78 , transient activation of NF-kappaB was observed with a peak at 6-12 h ; the activation subsided within 24 h despite the continuous absence of intact GRP78 ... These results suggested that loss of GRP78 by SubAB leads to transient phosphorylation of Akt and consequent activation of NF-kappaB through the ATF6 branch of the UPR
Lin et al., Cancer Res 1998 : Brefeldin A, an agent that disrupts protein transport from the endoplasmic reticulum to the Golgi, induces the expression of GRP78 and the activation of nuclear factor (NF)-kappaB in cells