Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
STAT3
→
Complex of PDGFRB-PDGFRB
(directlyIncreases, PDGFRB/PDGFRB Activity)
Heldin et al., Physiol Rev 1999 Evidence: I. Stat The family of Stat molecules has seven members of which Stat1, Stat3, Stat5a and -beta , and Stat6 have been shown to bind to the activated PDGF beta -receptor and to be phosphorylated after PDGF stimulation; binding also occurs to the alpha -receptor, albeit only weakly (347, 474, 482). After phosphorylation on tyrosine, Stats dimerize and translocate to the nucleus, where they act as transcription factors (reviewed in Ref. 92). Stat molecules are important for the transduction of signa...