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APOB — IL6

Text-mined interactions from Literome

Nishida et al., Kidney Int Suppl 1999 : Exposure to VLDL, IDL, LDL, or a high concentration of HDL enhanced the secretion of IL-6 , PDGF-AB, and TGF-beta by mesangial cells, whereas TNF-alpha secretion was stimulated by oxidized LDL
Massy et al., Biochem Biophys Res Commun 2000 : Therefore, we investigated the effects of native and oxidized LDL on human mesangial cell production of IL-6 and a possible modulation of this inflammatory response by lovastatin, which has been shown to ameliorate experimental glomerulosclerosis ... We found that native LDL stimulated 6 h mRNA expression and secretion of IL-6
Gierens et al., Arterioscler Thromb Vasc Biol 2000 (Hypercholesterolemia) : IL-6 dose-dependently increased the binding, internalization, and degradation of ( 125 ) I-LDL
Buechler et al., Biochim Biophys Acta 2003 (Coronary Artery Disease...) : Lipoprotein (a) downregulates lysosomal acid lipase and induces interleukin-6 in human blood monocytes
Tapiero et al., Biomed Pharmacother 2004 (Cardiovascular Diseases...) : In addition, Ox-LDL enhances the production and release of tumor necrosis factor ( TNF-alpha ), interleukin (IL)-6, arachidonic acid metabolites and nitric oxide ( NO ) that are responsible for various human pathologies including cancer
Choi et al., J Agric Food Chem 2009 : Conversely, oxidized LDL induced IL-6 release was minimal for the JAK2 activation, although this effect was counteracted by quercetin and rutin
Sparks et al., Am J Physiol Gastrointest Liver Physiol 2010 : Our objective was to evaluate IL-6 effects on hepatic apolipoprotein B (apoB) and VLDL secretion and to examine possible linkages between cytokine signaling and insulin-suppressive effects on lipoprotein secretion
Liu et al., J Cardiovasc Pharmacol 2012 (Atherosclerosis...) : In the effect of anti-inflammation, AN07 decreases the Ox-LDL stimulated upregulation of interleukin (IL) 1ß and IL-6 ... In addition, AN07 acts synergistically with rosiglitazone and pioglitazone to inhibit the Ox-LDL induced proliferation of human aortic smooth muscle cells and upregulation of cyclin D1, cyclin D3, IL-1ß, and IL-6
Lubrano et al., Indian J Med Res 2012 : The incubation with ox-LDL induced a significant increase in ICAM-1, IL-6 and ET-1 levels compared to the basal condition ( P < 0.01, P < 0.05, and P < 0.01, respectively ), while in presence of Lisosan G, ICAM-1 levels showed a significant reduction both compared to the cultures treated with ox-LDL and control ( P < 0.01 )
Wu et al., J Lipid Res 2012 (Hyperlipidemias) : Abundance of miR-181a attenuated ox-LDL induced CD83 and CD40 expression, inhibited the secretion of interleukin (IL)-6 and TNF-a, and up-regulated IL-10, an important anti-inflammatory cytokine that was inhibited by ox-LDL
Shaik-Dasthagirisaheb et al., Molecular oral microbiology 2013 : These data indicate that LDL affects the TNF-a and IL-6 response of macrophages to P. gingivalis challenge and that MyD88 and TRIF play important roles in P. gingivalis elicited foam cell formation
Kinoshita et al., Biochem Biophys Res Commun 2013 (Atherosclerosis) : In mouse peritoneal macrophages, apocynin suppressed the Ox-LDL induced ROS generation, mRNA expression of MCP-1, IL-6 and granulocyte/macrophage colony stimulating factor, and cell proliferation
Cheng et al., International journal of biological sciences 2013 : TLR4 siRNA showed stronger inhibition on AGE-LDL induced IL-6 and IL-8 production than that of TLR2 siRNA ... Silencing MyD88, but not TRIF, inhibited AGE-LDL induced IL-6 and IL-8 production ... Conclusion : AGE-LDL induced IL-6 and IL-8 production via TLR2/4-MyD88 dependent pathway in tubular epithelial cells
Nishida et al., Am J Kidney Dis 1997 : Exposure to VLDL, IDL, LDL, or a high concentration of HDL enhanced the secretion of interleukin-6 , platelet derived growth factor, and transforming growth factor-beta by mesangial cells, whereas tumor necrosis factor-alpha secretion was stimulated by oxidized LDL
Wooten et al., J Immunol 1998 : Lipoprotein mediated induction of nuclear factor-kappaB nuclear translocation and production of IL-8 and IL-6 in HUVEC was enhanced in the presence of serum or soluble rCD14
Bhakdi et al., Herz 1998 (Arteriosclerosis...) : In contrast, E-LDL does not stimulate IL-1 or TNF production and is only a weak inducer of IL-6