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CTSS — IL6

Text-mined interactions from Literome

Kitamura et al., Immunity 2005 : IL-6 mediated STAT3 activation decreased cystatin C level, an endogenous inhibitor of cathepsins , and enhanced cathepsin activities ... Overexpression of cystatin C suppressed IL-6-STAT3 mediated increase of cathepsin S activity and reduction of MHCII alphabeta dimer, Ii, and H2-DM levels in DCs ... Thus, IL-6-STAT3 mediated increase of cathepsin S activity reduces the MHCII alphabeta dimer, Ii, and H2-DM levels in DCs, and suppresses CD4 ( + ) T cell mediated immune responses
Baston-Buest et al., Reproduction 2010 : The invading embryo regulates the depth of its own invasion through the expression of the cathepsin inhibitors and furthermore, interleukin-6 to activate CTSS in maternal tissues
Caglič et al., Biol Chem 2013 : Stimulation of the cultivated chondrocytes with interleukin-1a and/or tumor necrosis factor a resulted in a time dependent increase in cathepsin S expression and induced its secretion into the conditioned media