Gene interactions and pathways from curated databases and text-mining

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IL3 — TBCC

Text-mined interactions from Literome

Jackson et al., Cell Transplant 2002 : The number of GM-CFC and HPP-CFC increased up to 3000- and 300-fold, respectively, after 7 days in IL-3- and SCF stimulated liquid culture
He et al., Haematologica 2010 : Neutralizing interleukin-3 in the aorta-gonad-mesonephros region resulted in reduced numbers of BL-CFC , indicating the physiological requirement for this cytokine
Williams et al., Blood 1990 : Thymidine suiciding studies suggest that this targeted infection is due to specific induction of cycling of CFC-Pre-B by IL-7 and CFU-GM by IL-3
McNiece et al., Exp Hematol 1987 : HPP-CFC-2 are stimulated by CSF-1 plus interleukin-3 and generate macrophage CFC that differentiate to form mature macrophages
Stewart et al., Blood 1993 (Hodgkin Disease...) : Multifactor combinations, especially GM-CSF + G-CSF + IL-3 + IL-6 + IL-1 + CSF-1 did not increase total colony count or classic HPP-CFC but did result in altered morphology, producing huge, loose colonies