Silver et al., Invest Ophthalmol Vis Sci 1999
(Autoimmune Diseases...) :
Unlike the B10.A strain in which appreciable disease did not develop without PTX, B10.RIII mice mounted a high IFN-gamma response to IRBP in the absence of PTX treatment
Takeuchi et al., Invest Ophthalmol Vis Sci 2010
(Behcet Syndrome...) :
IRBP stimulated IL-6, IFN-gamma , and IL-17 production was higher in BD patients than in healthy controls, though IL-10 production was not different between them ... In particular, IRBP stimulated IFN-gamma production was significantly higher in BD patients with active uveitis than in BD patients with uveitis in remission
Yokoi et al., Eur J Immunol 1997
(Autoimmune Diseases...) :
The proliferative response of splenocytes to IRBP in vitro was not significantly impaired, but the production of IL-2 and IFN-gamma was greatly reduced by the anti-IL-12 treatment