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IL13 — PDGFA
Text-mined interactions from Literome
Ingram et al., FASEB J 2004
(Fibrosis) :
Through the use of lung fibroblasts from STAT-6-deficient mice, we showed that
IL-13 induced
PDGF-AA release is STAT-6 dependent, but PDGF-AA induced growth is STAT-6 independent
Ingram et al., J Immunol 2006
:
IL-13 up-regulated
PDGF-A and PDGF-C mRNA levels in lung fibroblasts isolated from three different background strains of mice ... However,
IL-13 induced
PDGF-A and PDGF-C mRNA levels were significantly reduced in Stat6-deficient ( Stat6 ( -/- ) ) fibroblasts as compared with wild-type Stat6 ( +/+ ) fibroblasts ... In contrast,
IL-13 induced
PDGF-A and PDGF-C mRNAs were enhanced in Stat1 ( -/- ) fibroblasts as compared with Stat1 ( +/+ ) fibroblasts
Zhang et al., J Dermatol 1995
(Carcinoma, Squamous Cell) :
Prostaglandin E1 slightly inhibited PDGF-AB production, transforming growth factor beta 1
promoted PDGF-AB production and interferon-gamma,
interleukin-1 alpha, and tumor necrosis factor-alpha failed to exert any influence at all