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RAF1 — SLC22A3
Text-mined interactions from Literome
Wang et al., Oncogene 2004
:
These activities resemble those observed in
EMT induced by transforming growth factor (TGF)-beta1 or by
Ras-Raf signaling
Lan et al., Carcinogenesis 2004
:
Thus, oncogenic
Raf-1 regulates
EMT via distinct MAP kinase, p38 MAP kinase and c-Src tyrosine kinase signal pathways in the mouse hepatic cell line
Baritaki et al., Cell cycle (Georgetown, Tex.) 2010
(Neoplasms...) :
EMT induction is mediated, in part, by the constitutive activation of the metastasis-inducer transcription factor, Snail and EMT can be
inhibited by the metastasis-suppressor
Raf-1 kinase inhibitor protein (RKIP) and E-cadherin
Amatangelo et al., Carcinogenesis 2012
(Prostatic Neoplasms) :
Mechanistic studies revealed that in cells stably transfected with activated Ras, TGF-ß alone induced EMT and that a
Ras-Raf-MEK1 , but not MEK2, signaling cascade is
necessary and sufficient for Erk2 nuclear localization that works in concert with TGF-ß to promote
EMT