Chen et al., J Invest Dermatol 2013
(Psoriasis) :
mTORC2-PKBa/Akt1 Serine 473 Phosphorylation Axis Is Essential for Regulation of FOXP3 Stability by Chemokine CCL3 in Psoriasis
Zeng et al., Nature 2013
(Inflammation) :
By contrast, mTORC1 does not directly affect the expression of Foxp3 or anti- and pro-inflammatory cytokines in T ( reg ) cells, suggesting a non-conventional mechanism for T ( reg ) -cell functional regulation