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CD28 — IL18

Text-mined interactions from Literome

Okkenhaug et al., Nat Immunol 2001 : Nonetheless, this mutated form of CD28 still prevents the induction of anergy and promotes T cell proliferation, interleukin 2 secretion and B cell help
Karni et al., J Neuroimmunol 2002 (Multiple Sclerosis) : We found that anti-CD3/CD28 induced IL-18 production by peripheral blood mononuclear cells was increased in both relapsing remitting and secondary progressive MS
Ito et al., J Immunol 2003 (Encephalomyelitis, Autoimmune, Experimental) : MOG-specific T cells stimulated with anti-CD3 and anti-CD28 in the presence of IL-12 or IL-18 alone transferred only mild experimental autoimmune encephalomyelitis ( EAE ) into a low percentage of recipients
Abreu et al., Arthritis Res Ther 2010 (Arthritis, Experimental...) : Ex vivo, Rac1 inhibitory peptide suppressed T-cell receptor/CD28 dependent production of tumor necrosis factor alpha, interferon gamma and interleukin-17 by T cells from collagen primed mice, and reduced induction of ICOS and CD154, T-cell costimulatory proteins important for B-cell help