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GNA12 — SRC

Text-mined interactions from Literome

Klages et al., J Cell Biol 1999 : TXA2 receptor mediated activation of G12/G13 resulted in tyrosine phosphorylation of pp72 ( syk ) and stimulation of pp60(c-src) as well as in phosphorylation of myosin light chain ( MLC ) in Galphaq-deficient platelets
Nagao et al., Oncogene 1999 : Moreover, we observed that Galpha12Q229L stimulated Src family kinase activity and v-Src induced JNK activation
Sabath et al., J Cell Sci 2008 : Galpha12 ( GNA12 ) binds the TJ protein ZO-1 (TJP1), and Galpha12 activates Src to increase paracellular permeability via unknown mechanisms ... Inhibiting Hsp90 with geldanamycin blocks Galpha12 stimulated Src activation and phosphorylation, but does not affect protein levels or the Galpha12-ZO-1 interaction