Chang et al., Int J Mol Med 2011
(Peritoneal Fibrosis) :
The objective of the present study was to investigate the role of NADPH oxidase dependent formation of reactive oxygen species ( ROS ) in the angiotensin II (Ang II) induced epithelial-mesenchymal transition (EMT) and in the accumulation of extracellular matrix ( ECM ) in rat peritoneal mesothelial cells ( RPMCs ) ... In conclusion, NADPH oxidase dependent formation of ROS mediates Ang II dependent EMT and accumulation of ECM in rat peritoneal mesothelial cells
Liu et al., J Invest Dermatol 2012
(Melanoma...) :
Supplementing MMP-2 to culture media did not induce EMT, suggesting that EMT induction by Nox1 was not through MMP-2 upregulation