Gene interactions and pathways from curated databases and text-mining

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CA2 — SPP1

Text-mined interactions from Literome

Formigli et al., Am J Physiol Cell Physiol 2002 (Calcium Signaling) : In many cell systems, sphingosine 1-phosphate ( SPP ) increases cytosolic Ca2+ concentration ([Ca2+]i) by acting as intracellular mediator and extracellular ligand
Meyer zu Heringdrof et al., Naunyn Schmiedebergs Arch Pharmacol 1996 : In contrast to other [ Ca2+ ] i-elevating agonists, e.g., ATP and bradykinin, SPP did not activate phospholipase C in bovine aortic endothelial cells, suggesting the involvement of a novel, unidentified signalling pathway in SPP induced release of intracellular Ca2+
Törnquist et al., Am J Physiol 1997 : SPP stimulated the release of sequestered Ca2+ and a substantial entry of Ca2+