Chatterjee et al., Mol Carcinog 2001
:
Involvement of Fas receptor and not tumor necrosis factor-alpha receptor in ultraviolet induced activation of acid sphingomyelinase ... Fas receptor and tumor necrosis factor receptor-1 (TNFR1) mediate the activation of acid sphingomyelinase (ASMase) , which catalyzes the hydrolysis of sphingomyelin to ceramide
Dimanche-Boitrel et al., Drug Resist Updat 2005
:
Special attention is given to changes in plasma membrane fluidity, activation of the acid sphingomyelinase and the Fas death pathway in response to chemotherapy as well as their possible interrelationships
Cifone et al., EMBO J 1995
(Lymphoma) :
Activation of a phosphatidylcholine-specific phospholipase C ( PC-PLC ) was also detected which appeared to be a requirement for subsequent acidic sphingomyelinase (aSMase) activation, since PC-PLC inhibitor D609 blocked Fas/APO-1 induced aSMase activation, but not Fas/APO-1 induced neutral sphingomyelinase (nSMase) activation