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CD8B — HLA-DRA
Text-mined interactions from Literome
Heit et al., Eur J Immunol 2008
(Listeriosis) :
Since, in functional terms, this suppression by Treg largely exceeds the positive effects of conventional CD4 ( + ) T cell help, even the absence of all CD4 ( + ) T cells or lack of
MHC class II-mediated interactions on priming dendritic cells
result in enhanced
CD8 ( + ) T cell immunogenicity
Marodon et al., Eur J Immunol 1994
:
Thus, interaction of DP thymocytes with
MHC class II leads to the immediate down-regulation of
CD8 , which occurs simultaneously with an increase in TcR expression ; DPTcR ( lo ) HSA ( hi ) thymocytes mature into a CD4+CD8 ( lo ) TcR ( hi ) HSA ( hi ) intermediate population