Gene interactions and pathways from curated databases and text-mining

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BCL3 — MMP13

Text-mined interactions from Literome

Elliott et al., Arthritis Res Ther 2003 (Bone Neoplasms...) : Overexpression of Bcl-3 increased MMP-1, but not MMP-13 , mRNA levels
Lecoeur et al., Cell death & disease 2012 : Pharmacologic inhibitors of the permeability transition pore, Bax/Bak inhibitors, and recombinant Bcl-2 and Bcl-XL proteins do not reduce Tat induced MMP
Arbab et al., Evidence-based complementary and alternative medicine : eCAM 2012 : We found that dentatin mediated accumulation of reactive oxygen species ( ROS ) and downregulated expression levels of antiapoptotic molecules ( Bcl-2, Bcl-xL , and Survivin ), leading to disruption of mitochondrial membrane potential ( MMP ) , cell membrane permeability, and release of cytochrome c from the mitochondria into the cytosol