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NPY — PPY
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Parker et al., Peptides 2001
:
The
PP/NPY and Y4 receptors are also selectively
blocked by human or rat
pancreatic polypeptide (PP) and the blocking peptides are not dissociated by high concentrations of alkali chlorides ( which restore most of the binding of subtype-selective agonists to Y1 and Y2 sites )
Feth et al., Br J Pharmacol 1992
(Leukemia, Erythroblastic, Acute) :
NPY13-36 , vasoactive intestinal peptide (VIP) and
pancreatic polypeptide (PP) increased intracellular Ca2+ only poorly
Acuna-Goycolea et al., J Neurosci 2005
(Synaptic Transmission) :
Mechanisms of
neuropeptide Y , peptide YY, and
pancreatic polypeptide inhibition of identified green fluorescent protein expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus
Schlicker et al., Naunyn Schmiedebergs Arch Pharmacol 1991
:
The present results suggest that NPY inhibits serotonin release in the rat brain via presynaptic
NPY receptors, which are also
activated by PYY and
pancreatic polypeptide and may be negatively coupled to an adenylate cyclase
Balasubramaniam et al., Peptides 1990
:
Peptides unrelated to NPY did not compete with 125I-NPY for the binding sites even at 1 microM concentrations, whereas homologous peptides, peptide YY (PYY) and
pancreatic polypeptide (PP) , and NPY ( 13-36 )
inhibited 125I-NPY binding but with lower potency compared to NPY