Gene interactions and pathways from curated databases and text-mining

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MST1 — TNF

Text-mined interactions from Literome

Avitsur et al., Brain Behav Immun 2006 (Orthomyxoviridae Infections) : Interestingly, MSP induced increase in IL-1, TNF-alpha and IFN-gamma mRNA expression was evident in females, but not in males
Gunella et al., Br J Pharmacol 2006 (Pulmonary Fibrosis...) : Besides inducing interleukin-1 beta (IL-1beta) and interleukin-10 (IL-10) production, MSP triggers an enhanced tumor necrosis factor-alpha release, especially in healthy and pulmonary fibrosis smokers
Ohtsubo et al., Biochem Biophys Res Commun 2008 : Western blot analysis revealed that TNF-alpha induced activation of caspase 3 and Mst1 in a time- and dose dependent manner ... TNF-alpha induced Mst1 activation is almost completely prevented by pretreatment with Z-DEVD-FMK, a caspase 3 inhibitor ... Diphenyleneiodonium, an inhibitor of NADPH oxidase, and N-acetylcysteine, a potent antioxidant, also inhibited TNF-alpha induced activation of Mst1 and caspase 3, as well as apoptosis
Tong et al., Inflamm Res 2011 (Arthritis, Rheumatoid) : MSP markedly inhibited expression of inflammatory cytokines ( IL-1ß, TNF-a and IL-18 ), chemokines ( MIP-1, MCP-1 and RANTES ) and iNOS, NO, COX-2 and PGE ( 2 ) in RASF stimulated by LPS
Ruan et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2012 : Silencing of MST1 expression by siRNA diminishes TNF-a mediated human umbilical vein endothelial cell apoptosis by inhibiting the cascade effect of caspase-3