Gene interactions and pathways from curated databases and text-mining

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RHO — TNF

Text-mined interactions from Literome

Tramontano et al., Biochem Biophys Res Commun 2004 : Fluvastatin suppressed TNF-alpha induced Rho activation
Ito et al., Spine (Phila Pa 1976) 2007 (Disease Models, Animal...) : Furthermore, it is thought that Rho is involved in TNF-alpha and interleukin ( IL ) production in the central nervous system, and the production was inhibited by administering Rho kinase inhibitor in the central nervous system
Mong et al., J Immunol 2008 (Pneumonia) : Inhibition of RhoA protein expression using small interfering RNA, however, did not prevent TNF-alpha induced Rho kinase activation or JNK activation
Kakiashvili et al., J Biol Chem 2009 : GEF-H1 mediates tumor necrosis factor-alpha induced Rho activation and myosin phosphorylation : role in the regulation of tubular paracellular permeability ... Tumor necrosis factor-alpha (TNF-alpha) , an inflammatory cytokine, has been shown to activate the small GTPase Rho , but the underlying signaling mechanisms remained undefined
Tabibzadeh et al., Endocrine 1995 : Dyscohesion induced by this cytokine is associated with perturbation of the actin cytoskeleton which may be due to the regulatory role of TNF-a on Rho
Yasui et al., Microbiol Immunol 2011 : The activation of Rho and focal adhesion kinases induced by TNF-a stimulation might be linked to cell assembling and the formation of Langhans-type MGCs. MGCs can produce only small amounts of superoxide anions compared to isolated macrophages such as myeloid DCs