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RHO — TNF
Text-mined interactions from Literome
Tramontano et al., Biochem Biophys Res Commun 2004
:
Fluvastatin suppressed
TNF-alpha induced
Rho activation
Ito et al., Spine (Phila Pa 1976) 2007
(Disease Models, Animal...) :
Furthermore, it is thought that
Rho is
involved in
TNF-alpha and interleukin ( IL ) production in the central nervous system, and the production was inhibited by administering Rho kinase inhibitor in the central nervous system
Mong et al., J Immunol 2008
(Pneumonia) :
Inhibition of RhoA protein expression using small interfering RNA, however, did not prevent
TNF-alpha induced
Rho kinase activation or JNK activation
Kakiashvili et al., J Biol Chem 2009
:
GEF-H1 mediates
tumor necrosis factor-alpha induced
Rho activation and myosin phosphorylation : role in the regulation of tubular paracellular permeability ...
Tumor necrosis factor-alpha (TNF-alpha) , an inflammatory cytokine, has been shown to
activate the small GTPase
Rho , but the underlying signaling mechanisms remained undefined
Tabibzadeh et al., Endocrine 1995
:
Dyscohesion induced by this cytokine is associated with perturbation of the actin cytoskeleton which may be due to the regulatory
role of
TNF-a on
Rho
Yasui et al., Microbiol Immunol 2011
:
The activation of
Rho and focal adhesion kinases
induced by
TNF-a stimulation might be linked to cell assembling and the formation of Langhans-type MGCs. MGCs can produce only small amounts of superoxide anions compared to isolated macrophages such as myeloid DCs