Gene interactions and pathways from curated databases and text-mining

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BMP2 — BMPER

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Binnerts et al., Biochem Biophys Res Commun 2004 : These results suggest that hCV-2 may regulate BMP responsiveness of osteoblasts and chondrocytes in vivo
Heinke et al., Circ Res 2008 : Vice versa, BMP-4 is necessary for BMPER activity
Kelley et al., J Cell Biol 2009 : Both pro- and anti-Bmp activities have been postulated for Bmper, although the molecular mechanisms through which Bmper affects Bmp signaling are unclear ... This dosage dependent molecular switch resolves discordances among studies that examine how Bmper regulates Bmp activity and has broad implications for Bmp signal regulation by secreted mediators
Pi et al., Circ Res 2012 : Among the extracellular modulators of Bmp ( bone morphogenetic protein ) signaling, Bmper ( Bmp endothelial cell precursor derived regulator ) both enhances and inhibits Bmp signaling
Cao et al., Development 2013 : In addition, miR-203 expression was activated by endogenous Pitx2 and targeted the Bmp antagonist Bmper to further regulate Bmp signaling