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JAG1 — MYLIP

Text-mined interactions from Literome

Ahluwalia et al., RNA Biol 2012 : Here we report the validation of miRNA-target interactions we predicted earlier and demonstrate the regulation of endogenous JAG1 by hsa-miR-214 and hsa-miR-124 , and TGFBR2 by hsa-miR-34b*, through luciferase activity of reporter constructs and also the expression levels of the endogenous genes
Selcuklu et al., Biochem Biophys Res Commun 2012 (Breast Neoplasms) : We demonstrate ( by ablation of the miR-21 binding site in the JAG1 3'UTR ) that miR-21 directly targets and represses JAG1 levels in MCF-7 ( ER+ ) breast cancer cells
Holman et al., PloS one 2012 : We cloned the full length 3'UTR of Amex-Jag1, and our in vitro assays demonstrated that its single miR-21 target recognition site is functional and essential for the response of the Jagged1 gene to miR-21 levels